Evaluation of Dot. ELISA test for Diagnosis Visceral Leishmaniasis in Infected Children
| Autor: | W. R. Ali, R. S. Al-Sady, A. A. J. J. Al- Saadi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Ibn Al-Haitham Journal for Pure and Applied Sciences, Vol 22, Iss 4 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1609-4042 2521-3407 |
| Popis: | For the first time in Iraq, this study was conducted to evaluate the usefulness of Dot.ELISA, for detecting anti - Leishmania donovani antibodies in serum samples from suspected patient (children under 8 years ) with Visceral Leishmaniasis V.L.. Sera from 73 V.L. , 60 Healthy controls, and 57 patient with other parasitic diseases other than V.L. (Amoebiasis, Giardiasis , Toxoplasmosis, Schistosomiasis , Hydatidosis, Ascariasis , Lupus Erythromatosus , Viral Hepatitis, and Cutaneous Leishmaniasis) were examined. Anti Leishmania donovani antibodies detected in 71 out of 73 suspected Visceral Leishmaniasis . Data of this study showed that infection in male group was more than female group. Result of this study revealed a high prevalence of patients with V.L. infection at the age range 1 - 2.9 and 3 - 4.9 years when compared with other range groups (P>0.01). A cross – reaction was found with sera Lupus Erythromatosus, No cross - reaction was found with sera from other disease . Sensitivity was determined as 97.3 %, and Specificity was found to be 95.7% . Positive and Negative the Values Predictive of test were 96% and 97.4% Dot .ELISA is simpler, Serodiagnosis Rapid, sensitive and specific, Its use in respectively. Seeing that of V.L. can be recommended. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|