| Autor: |
Miyahara Ryoji, Nakamura Masanao, Miyake Nobuyuki, Maeda Osamu, Ishiguro Kazuhiro, Watanabe Osamu, Ando Takafumi, Ishikawa Daisuke, Ohmiya Naoki, Hirooka Yoshiki, El-Omar Emad M, Goto Hidemi |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
BMC Gastroenterology, Vol 11, Iss 1, p 29 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
1471-230X |
| DOI: |
10.1186/1471-230X-11-29 |
| Popis: |
Abstract Background Real-time tissue sonoelastography (EG) is a new non-invasive technique that visualizes differences in tissue strain. We evaluated the usefulness of EG in patients with ulcerative colitis (UC) by investigating the association between EG and colonoscopic findings and disease activity. Methods Thirty-seven UC patients undergoing EG and colonoscopy were invited to enroll. EG findings were classified as normal, homogeneous, random, or hard, and colonoscopic findings as normal, mucosal edema and erosion, punched-out ulcer, and extensive mucosal abrasion. Clinical findings were evaluated using clinical activity index (CAI) scores for each patient at colonoscopy. Results On EG, 10 cases were classified as normal, 11 as homogeneous, 6 as random, and 10 as hard. EG findings showed a significant correlation those of colonoscopy (p < 0.001). Seven of 10 (70%) normal-type patients were in the remission phase, while all 6 random-type patients were in the active phase. Among active-phase patients, 4 of 7 (57%) homogeneous-type patients responded to steroid or leukocytapheresis therapy, while 3 of 6 (50%) random-type patients required treatment with cyclosporine. Three of 10 (30%) hard-type patients required colectomy. Conclusions In this small series, EG findings reflected colonoscopic findings and correlated with disease activity among patients with UC. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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