Increased serum calcium levels are associated with carotid atherosclerotic plaque in normocalcaemic individuals with type 2 diabetes
Autor: | Huijing Zhu, Huili Wang, Yuqing Jia, Lin Cheng, Xingbo Cheng |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Therapeutic Advances in Endocrinology and Metabolism, Vol 12 (2021) |
Druh dokumentu: | article |
ISSN: | 2042-0196 20420188 |
DOI: | 10.1177/2042018821995369 |
Popis: | Background: Patients with type 2 diabetes mellitus (T2DM) have an elevated risk of atherosclerotic cardiovascular disease. Although previous data have suggested that serum calcium levels could be involved in T2DM and cardiovascular disease, whether this applies in T2DM patients with atherosclerosis remains unclear. This study therefore aimed to investigate the relationship between serum calcium levels within the physiological ranges and carotid atherosclerotic plaque in T2DM patients. Methods: A total of 594 normocalcaemic in-patients with T2DM were recruited, of whom 231 had carotid atherosclerotic plaque. Serum calcium levels were measured and carotid ultrasonography was performed. Results: Patients with plaque had significantly higher serum albumin-corrected calcium than those without plaque [9.02 (8.78–9.34) mg/dL versus 8.86 (8.66–9.06) mg/dL, p |
Databáze: | Directory of Open Access Journals |
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