Traditional uses and pharmacological properties of Clerodendrum phytochemicals

Autor: Jin-Hui Wang, Fei Luan, Xiang-Dong He, Yong Wang, Mao-Xing Li
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Traditional and Complementary Medicine, Vol 8, Iss 1, Pp 24-38 (2018)
Druh dokumentu: article
ISSN: 2225-4110
DOI: 10.1016/j.jtcme.2017.04.001
Popis: Clerodendrum is a genus of ca. 500 species in the family Lamiaceae and widely distributed throughout the whole world. Up to now, many species of this genus have been described in various indigenous systems of medicine and are used in preparation of folklore medicines for the treatment of various life-threatening diseases, and more than eleven species of the Clerodendrum genus have been very well studied for their chemical constituents and biological activities, and 283 compounds, including monoterpene and its derivatives, sesquiterpene, diterpenoids, triterpenoids, flavonoid and flavonoid glycosides, phenylethanoid glycosides, steroids and steroid glycosides, cyclohexylethanoids, anthraquinones, cyanogenic glycosides, and others have been isolated and identified. Pharmacological studies have shown that these compounds and extracts from the Clerodendrum genus have extensive activities, such as anti-inflammatory and anti-nociceptive, anti-oxidant, anti-hypertensive, anticancer, antimicrobial, anti-diarrheal, hepatoprotective, hypoglycemic and hypolipidemic, memory enhancing and neuroprotective, and other activities. In this review, we attempt to highlight over phytochemical progress and list the phytoconstituents isolated from the genus Clerodendrum reported so far. The biological activities of this genus are also covered.
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