Hidden reach of the micromanagers

Autor: Jackson Aimee L, Linsley Peter S
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: BMC Biology, Vol 8, Iss 1, p 53 (2010)
Druh dokumentu: article
ISSN: 1741-7007
DOI: 10.1186/1741-7007-8-53
Popis: Abstract Small interfering RNAs can trigger unintended, microRNA-like off-target effects, but the impact of these effects on functional studies has been controversial. A recent study in BMC Genomics shows that microRNA-like effects can predominate among the 'hits' of functional genomics screens. See research article http://www.biomedcentral.com/1471-2164/11/175
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