| Autor: |
Elisenda Climent, Ana Rodriguez-Campello, Joan Jiménez-Balado, Mercè Fernández-Miró, Jordi Jiménez-Conde, Gemma Llauradó, Ángel Ois, Juana A. Flores, Elisa Cuadrado-Godia, Eva Giralt Steinhauer, Juan J. Chillarón, Neurovascular Research Group (NEUVAS) |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-9 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1475-2840 |
| DOI: |
10.1186/s12933-024-02260-9 |
| Popis: |
Abstract Objective Elevated plasma glucose levels are common in patients suffering acute ischemic stroke (AIS), and acute hyperglycemia has been defined as an independent determinant of adverse outcomes. The impact of acute-to-chronic glycemic ratio (ACR) has been analyzed in other diseases, but its impact on AIS prognosis remains unclear. The main aim of this study was to assess whether the ACR was associated with a 3-month poor prognosis in patients with AIS. Research, design and methods Retrospective analysis of patients admitted for AIS in Hospital del Mar, Barcelona. To estimate the chronic glucose levels (CGL) we used the formula eCGL= [28.7xHbA1c (%)]-46.7. The ACR (glycemic at admission / eCGL) was calculated for all subjects. Tertile 1 was defined as: 0.28–0.92, tertile 2: 0.92–1.13 and tertile 3: > 1.13. Poor prognosis at 3 months after stroke was defined as mRS score 3–6. Results 2.774 subjects with AIS diagnosis were included. Age, presence of diabetes, previous disability (mRS), initial severity (NIHSS) and revascularization therapy were associated with poor prognosis (p values |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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