Antimicrobial Activity of Penicillin G and N-acetylcystein on Planktonic and Sessile Cells of Streptococcus suis

Autor: Ivette Espinosa, Michel Báez, Evelyn Lobo, Siomara Martínez, Marcelo Gottschalk
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Polish Journal of Microbiology, Vol 65, Iss 1 (2016)
Druh dokumentu: article
ISSN: 17331331
1733-1331
2544-4646
DOI: 10.5604/17331331.1197282
Popis: The aim of this study was to investigate the capacity of Streptococcus suis strains to form biofilms and to evaluate the antimicrobial activity of Penicillin G and N-acetylcystein (NAC) on both S. suis sessile and planktonic forms. Only non-typeable isolates of S. suis were correlated with a greater biofilm formation capacity. The MCI of Penicillin G and NAC required for inhibiting biofilm growth were higher than the required concentration for inhibiting planktonic growth. The combinations of NAC and Penicillin G showed a strong synergistic activity that inhibited biofilm formation and disrupted the pre-formed biofilm of S. suis.
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