Early‐onset interstitial pneumonitis in a patient with advanced non‐small cell lung cancer treated with crizotinib and osimertinib

Autor:	Yuan Cheng, Qing Yu, Yan Xiong, Cuiyan Guo, Ligong Nie
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Crizotinib early‐onset interstitial pneumonitis NSCLC Osimertinib Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Thoracic Cancer, Vol 12, Iss 5, Pp 690-692 (2021)
Druh dokumentu:	article
ISSN:	1759-7714 1759-7706
DOI:	10.1111/1759-7714.13785
Popis:	Both crizotinib and osimertinib have been reported to have an adverse effect of interstitial pneumonitis in the treatment of non‐small cell lung cancer (NSCLC). Here, we report the case of a 60‐year‐old male patient with advanced NSCLC resistant to osimertinib. Crizotinib was administered in combination with osimertinib due to elevated mesenchymal epithelial transition (MET) copy number amplification. However, early‐onset interstitial pneumonitis occurred within two days.
Databáze:	Directory of Open Access Journals
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