NLR, MPV and RDW as Biomarkers in Operated and Non-operated Patients with Colorectal Adenocarcinoma

Autor: Atilla Bulur, Ayça Serap Çakır
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Bagcilar Medical Bulletin, Vol 6, Iss 3, Pp 314-319 (2021)
Druh dokumentu: article
ISSN: 2547-9431
DOI: 10.4274/BMB.galenos.2021.05.056
Popis: Objective:There is a need for inexpensive, reliable and readily available biomarkers in the early diagnosis and prediction of mortality, morbidity and treatment response in colorectal cancer (CRC). In our study, it was aimed to compare mean platelet volume (MPV), red cell distribution width (RDW) and neutrophil-lymphocyte ratio (NLR) measurements in operated and non-operated patients with the diagnosis of CRC.Method:In our study, we retrospectively reviewed 52 patients (including 26 operated patients and 26 non-operated patients) diagnosed as CRC with colonoscopic biopsy at endoscopy unit of gastroenterology department between 2016 and 2019. We extracted and compared demographic, colonoscopy, clinical, laboratory and surgical data in both groups.Results:In our study, the mean age (60.04 years and 64.19 years, respectively) and gender distribution (female: male, 12: 14 and 11: 15, respectively) were comparable in operated and non-operated patients with CRC. MPV, RDW and NLR measurements were found to be significantly lower in patients who underwent surgery (operated) when compared to non-operated patients (p
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