Echocardiographic evidence of left ventricular untwisting-filling interplay

Autor: Amir Hodzic, Damien Garcia, Eric Saloux, Paula A. B. Ribeiro, Amélie Ethier, James D. Thomas, Paul Milliez, Hervé Normand, Francois Tournoux
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Cardiovascular Ultrasound, Vol 18, Iss 1, Pp 1-12 (2020)
Druh dokumentu: article
ISSN: 1476-7120
DOI: 10.1186/s12947-020-00190-6
Popis: Abstract Background Left ventricular untwisting generates an early diastolic intraventricular pressure gradient (DIVPG) than can be quantified by echocardiography. We sought to confirm the quantitative relationship between peak untwisting rate and peak DIVPG in a large adult population. Methods From our echocardiographic database, we retrieved all the echocardiograms with a normal left ventricular ejection fraction, for whom color Doppler M-Mode interrogation of mitral inflow was available, and left ventricular untwisting rate was measurable using speckle tracking. Standard indices of left ventricular early diastolic function were assessed by Doppler (peaks E, e’ and Vp) and speckle tracking (peak strain rate Esr). Load dependency of DIVPG and untwisting rate was evaluated using a passive leg raising maneuver. Results We included 154 subjects, aged between 18 to 77 years old, 63% were male. Test-retest reliability for color Doppler-derived DIVPG measurements was good, the intraclass correlation coefficients were 0.97 [0.91–0.99] and 0.97 [0.67–0.99] for intra- and inter-observer reproducibility, respectively. Peak DIVPG was positively correlated with peak untwisting rate (r = 0.73, P
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