Sterol synthesis. A simplified method for the synthesis of 32-oxygenated derivatives of 24,25-dihydrolanosterol.
| Autor: | E J Parish, G J Schroepfer, Jr |
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| Jazyk: | angličtina |
| Rok vydání: | 1981 |
| Předmět: | |
| Zdroj: | Journal of Lipid Research, Vol 22, Iss 5, Pp 859-868 (1981) |
| Druh dokumentu: | article |
| ISSN: | 0022-2275 |
| DOI: | 10.1016/S0022-2275(20)37358-2 |
| Popis: | A simplified method is described for the preparation of 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-8-en-e beta-ol, 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-7-en-3 beta-ol, and 14 alpha-hydroxymethyl-4,4-dimethyl-5-alpha-cholest-6-en-3 beta-ol from commercial lanosterol. This method represents a modification of the approach introduced by Fried and co-workers (Fried, J., J. W. Brown, and L. Borkenhagen. 1965. Tetrahedron Lett. 2499-2504). |
| Databáze: | Directory of Open Access Journals |
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