A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report

Autor: Minu George, Neena Baby, Pradeep Mathew Koshy, Rajendran Ullatil, Sureshkumar Radhakrishnan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 7, Pp 332-334 (2022)
Druh dokumentu: article
ISSN: 2352-4146
1995-7645
DOI: 10.4103/1995-7645.351765
Popis: Rationale: To report a case of cervicobrachial variant of acute inflammatory demyelinating polyneuropathy presenting with papilledema and GQ1b positivity. Patient concern: A 35-year-old female, 68 days postpartum, presented with headache, vomiting, and gait difficulty in swallowing with bilateral upper limb weakness and difficulty in walking, 13 days after ChAdOx1 nCoV-19 vaccination. Diagnosis: Guillain-Barre syndrome with GQ1b positivity. Intervention: Five cycles of plasmapheresis were given. Outcome: The patient’s clinical condition improved. Palatal weakness improved and she could walk without support. There were mild sensory symptoms involving upper limbs which gradually improved. Lessons: AIDP should be considered in case of weakness following ChAdOx1 nCoV-19 vaccination. Albumino-cytological dissociation and anti-GQ1b positivity are needed to confirmed the diagnosis.
Databáze: Directory of Open Access Journals