Quantitative characterization of 3D bioprinted structural elements under cell generated forces

Autor: Cameron D. Morley, S. Tori Ellison, Tapomoy Bhattacharjee, Christopher S. O’Bryan, Yifan Zhang, Kourtney F. Smith, Christopher P. Kabb, Mathew Sebastian, Ginger L. Moore, Kyle D. Schulze, Sean Niemi, W. Gregory Sawyer, David D. Tran, Duane A. Mitchell, Brent S. Sumerlin, Catherine T. Flores, Thomas E. Angelini
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-10919-1
Popis: Advances in biofabrication technology enable 3D printed constructs to resemble real tissues, but it remains unclear how cell-generated forces deform these constructs. Here the authors investigate mechanical behaviours of 3D printed “microbeams” made from mixtures of living cells and extracellular matrix.
Databáze: Directory of Open Access Journals