Optical Coherence Tomography Angiography Findings in Stargardt Disease.

Autor: Rodolfo Mastropasqua, Lisa Toto, Enrico Borrelli, Luca Di Antonio, Peter A Mattei, Alfonso Senatore, Marta Di Nicola, Cesare Mariotti
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: PLoS ONE, Vol 12, Iss 2, p e0170343 (2017)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0170343
Popis: BACKGROUND:to assess vessel density of superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris (CC) in advanced Stargardt disease (STGD) using optical coherence tomography angiography (OCTA) and correlate these findings with macular function using pattern electroretinogram (PERG) and multifocal electroretinogram (mfERG). METHODS:Twelve patients (24 eyes) with advanced STGD underwent vessel densities and macular thickness measurements using OCTA. A control group of 24 healthy controls (24 eyes) was chosen for comparison. In the STGD group correlation between vessel density and macular thickness and between macular function and morphologic parameters were evaluated. RESULTS:Whole parafoveal vessel density (VD) of SCP was significantly lower in STGD group compared to the control group (p
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