Meta-analysis of the correlation between high expression of lncRNA NEAT1 in rectal cancer and pathological features and prognosis

Autor: Lin Qiyi, Pan Jianpeng, Wang Huaishuai, Li Yinlin, Zhuang Yixiang, Cai Zhicong, Lin Gaofeng, Liu Weibo, Xu Guoxi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Medical Biochemistry, Vol 43, Iss 4, Pp 503-511 (2024)
Druh dokumentu: article
ISSN: 1452-8258
1452-8266
DOI: 10.5937/jomb0-47889
Popis: Background: To systematically evaluate the relationship between the expression level of long noncoding RNA NEAT1 and the clinical characteristics and prognostic value of rectal cancer patients. Methods: PubMed, EMBASE, Cochrane library database and case-control studies on the correlation between abnormal expression of lncRNA NEAT1 and prognosis of rectal cancer patients published by the American clinical trials registry before May 1, 2023 were searched. The search time was from the establishment of the database to May 30, 2023. Results: A total of 7 case-control studies were included, including 1063 cancer patients. The results of meta-analysis showed that the high expression of lncRNA NEAT1 was significantly correlated with the degree of differentiation [or=0.45, 95%CI=0.32-0.63, P
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