Supramammillary glutamate neurons are a key node of the arousal system

Autor: Nigel P. Pedersen, Loris Ferrari, Anne Venner, Joshua L. Wang, Stephen B. G. Abbott, Nina Vujovic, Elda Arrigoni, Clifford B. Saper, Patrick M. Fuller
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-01004-6
Popis: Supramammillary nucleus (SuM) neurons have been studied in the context of REM sleep but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional contributions of three subpopulations in the SuM on electrographical and behavioral arousal in mice using genetically targeted approaches.
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