Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis

Autor: Ayaka Ito, Shinichi Iwata, Soichiro Tamura, Andrew T. Kim, Shinichi Nonin, Sera Ishikawa, Asahiro Ito, Yasuhiro Izumiya, Takato Abe, Toshihiko Shibata, Minoru Yoshiyama
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Cerebrovascular Diseases Extra, Vol 10, Iss 3, Pp 116-123 (2020)
Druh dokumentu: article
ISSN: 1664-5456
DOI: 10.1159/000510438
Popis: Introduction: Silent brain infarction (SBI) is an independent risk factor for subsequent symptomatic stroke in the general population. Although aortic stenosis (AS) is also known to be associated with an increased risk of future symptomatic stroke, little is known regarding the prevalence and risk factors for SBI in patients with AS. Methods: The study population comprised 83 patients with severe AS with no history of stroke or transient ischemic attack and paralysis or sensory impairment (mean age 75 ± 7 years). All patients underwent brain magnetic resonance imaging to screen for SBI and multidetector-row computed tomography to quantify the aortic valve calcification (AVC) volume. Comprehensive transthoracic and transesophageal echocardiography were performed to evaluate left atrial (LA) abnormalities, such as LA enlargement, spontaneous echo contrast, or abnormal LA appendage emptying velocity (
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