Altered spontaneous brain activities in maintenance hemodialysis patients with cognitive impairment and the construction of cognitive function prediction models

Autor:	Qing Sun, Jiahui Zheng, Yutao Zhang, Xiangxiang Wu, Zhuqing Jiao, Lifang Xu, Haifeng Shi, Tongqiang Liu
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Resting-state magnetic resonance imaging maintenance hemodialysis cognitive impairment low-frequency amplitude ratiometric low-frequency amplitude regional homogeneity Diseases of the genitourinary system. Urology RC870-923
Zdroj:	Renal Failure, Vol 45, Iss 1 (2023)
Druh dokumentu:	article
ISSN:	0886022X 1525-6049 0886-022X
DOI:	10.1080/0886022X.2023.2217276
Popis:	AbstractObjective The brain neuromechanism in maintenance hemodialysis patients (MHD) with cognitive impairment (CI) remains unclear. The study aimed to probe the relationship between spontaneous brain activity and CI by using resting-state functional magnetic resonance imaging (rs-fMRI) data.Methods Here, 55 MHD patients with CI and 28 healthy controls were recruited. For baseline data, qualitative data were compared between groups using the χ2 test; quantitative data were compared between groups using the independent samples t-test, ANOVA test, Mann–Whitney U-test, or Kruskal–Wallis test. Comparisons of ALFF/fALFF/ReHo values among the three groups were calculated by using the DPABI toolbox, and then analyzing the correlation with clinical variables. p
Databáze:	Directory of Open Access Journals
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