miRNAs: Biogenesis, Origin and Evolution, Functions on Virus-Host Interaction

Autor: Yang Zhuo, Guohui Gao, Jian an Shi, Xuexue Zhou, Xiaofeng Wang
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 499-510 (2013)
Druh dokumentu: article
ISSN: 1015-8987
1421-9778
DOI: 10.1159/000354455
Popis: MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs. They can play vital roles in post-transcriptional regulating mRNAs transcripts in nearly all biological processes. More and more reports on miRNAs come from different species (animal, plant, bacteria, virus) in the researches in development, immunity, apoptosis, tumor, virus-host interaction. These recent findings provide new insights into the roles of miRNAs as well as their function. This review outlines the ever-deepening understanding of miRNAs (biogenesis, origin, evolution), and discusses functions from host and viral miRNAs in the context of virus-host interaction.
Databáze: Directory of Open Access Journals