Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial Vaginosis
| Autor: | Caroline Mitchell, Carla Moreira, David Fredricks, Kathleen Paul, Angela M. Caliendo, Jaclynn Kurpewski, Jessica Ingersoll, Susan Cu-Uvin |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Infectious Diseases in Obstetrics and Gynecology, Vol 2009 (2009) |
| Druh dokumentu: | article |
| ISSN: | 1064-7449 1098-0997 |
| DOI: | 10.1155/2009/236919 |
| Popis: | Background. Fastidious bacteria have been associated with bacterial vaginosis (BV) using PCR methods. We assessed the prevalence of these bacteria in HIV-1 infected women and their relationship with vaginal pH and shedding of HIV-1 RNA. Methods. 64 cervicovaginal lavage (CVL) samples were collected from 51 women. Vaginal microbiota were characterized using 8 bacterium-specific quantitative PCR assays. Results. Women with the fastidious bacteria Bacterial Vaginosis Associated Bacterium (BVAB) 1, 2, and 3 showed a trend to increased HIV-1 shedding (OR 2.59–3.07, P=.14–.17). Absence of Lactobacillus crispatus (P |
| Databáze: | Directory of Open Access Journals |
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