Minimal within-day variation of high density lipoprotein cholesterol and apolipoprotein A-I levels in normal subjects

Autor: L O Henderson, A L Saritelli, E LaGarde, P N Herbert, R S Shulman
Jazyk: angličtina
Rok vydání: 1980
Předmět:
Zdroj: Journal of Lipid Research, Vol 21, Iss 7, Pp 953-955 (1980)
Druh dokumentu: article
ISSN: 0022-2275
DOI: 10.1016/S0022-2275(20)34793-3
Popis: Blood was drawn from twenty normal hospital employees after a 12-14 hr fast (9:30 AM), and at 4 hr (1:30 PM) and 7 hr (4:30 PM) thereafter while test subjects consumed their habitual diet. Absorptive chylomicronemia was reflected in average triglyceride increases of 30% and 53% at 4 hr and 7 hr, respectively. No significant changes in total (< 1%) and high density lipoprotein (< 0.1%) cholesterol concentrations were observed. Moreover, levels of the major high density lipoprotein apolipoprotein, apoA-I, varied by less than 3%. Blood samples, randomly obtained during standard working hours, appear adequate for quantitation of high density lipoprotein cholesterol and apolipoprotein A-I levels.
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