| Autor: |
Diwakar Shukla, Ariana Peck, Vijay S. Pande |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms10910 |
| Popis: |
Calmodulin is an important calcium sensor that can recognise and interact with a large range of proteins. Here, the authors use molecular dynamics simulations and Markov state models to show that the range of binding conformations adopted without substrate can help explain its diverse and specific binding. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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