Trends of Pancreatic Cancer Incidence and Mortality in Changning District of Shanghai

Autor: FANG Jie, WANG Jie, LI Honglan, FENG Guoshan, WU Hua, JIANG Yufei, JIANG Yu, ZHANG Lei, ZHANG Yun, ZHOU Peng, XIA Qinghua, ZHAO Wensui, XIANG Yongbing
Jazyk: čínština
Rok vydání: 2021
Předmět:
Zdroj: Zhongliu Fangzhi Yanjiu, Vol 48, Iss 7, Pp 727-732 (2021)
Druh dokumentu: article
ISSN: 1000-8578
DOI: 10.3971/j.issn.1000-8578.2021.20.1116
Popis: Objective To analyze the secular trends of pancreatic cancer incidence and mortality in Changning district of Shanghai from 1974 to 2013. Methods We calculated the age-standardized rates of incidence and mortality and the average annual percent changes for pancreatic cancer using Segi's world standard population and the data from Shanghai Cancer Registry. Age-period-cohort model was constructed to further assess the effect of age, diagnosis period and birth cohort on the secular trends of pancreatic cancer incidence and mortality. Results During 1974-2013, the age-standardized incidence and mortality rates were 6.49/105 and 6.01/105 in male, 4.83/105 and 4.57/105 in female, respectively. The age-standardized incidence was increased by 0.8% per year in male during past 40 years, while there was no change in mortality. The age-standardized incidence and mortality rates were increased by 1.6% and 1.3% per year in female. After adjusting the effects of diagnosis period and birth cohort, the incidence and mortality rates of pancreatic cancer increased by about 11% every 5 years older in both male and female. Diagnosis period and birth cohort had no statistical impact on the incidence and mortality of pancreatic cancer. Conclusion The age-standardized incidence of pancreatic cancer shows significantly rising trends during 1974-2013 in both male and female in Changning district of Shanghai, as well as the age-standardized mortality in female. The incidence and mortality rates also increase with age.
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