Baseline liver steatosis has no impact on liver metastases and overall survival in rectal cancer patients

Autor: Giulia Besutti, Angela Damato, Francesco Venturelli, Candida Bonelli, Massimo Vicentini, Filippo Monelli, Pamela Mancuso, Guido Ligabue, Pierpaolo Pattacini, Carmine Pinto, Paolo Giorgi Rossi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-021-07980-9
Popis: Abstract Background The liver is one of the most frequent sites of metastases in rectal cancer. This study aimed to evaluate how the development of synchronous or metachronous liver metastasis and overall survival are impacted by baseline liver steatosis and chemotherapy-induced liver damage in rectal cancer patients. Methods Patients diagnosed with stage II to IV rectal cancer between 2010 and 2016 in our province with suitable baseline CT scan were included. Data on cancer diagnosis, staging, therapy, outcomes and liver function were collected. CT scans were retrospectively reviewed to assess baseline steatosis (liver density
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