Mechanisms of scar formation and research progress in anti-fibrosis therapy after glaucoma filtration surgery

Autor: Ya-Nan Kong, Hong Lu, Ying Chen, Na Li, Xing-Xing Liu
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 19, Iss 10, Pp 1688-1691 (2019)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2019.10.12
Popis: Filtering channels carring and subsequent obstruction are the main cause of operation failure after glaucoma filtration surgery. During the process of scarring, human Tenon fibroblasts are transformed into myofibroblasts and secrete a large amount of extracellular matrixproteins. The derangement of the collagen fiber is also observed. A large number of studies have been carried out by domestic and foreign researchers on the treatment of postoperative filtering channel scarring. In this review we summarize the mechanisms of scar formation after glaucoma filtration surgery and corresponding research progress in recent years.
Databáze: Directory of Open Access Journals