The influence of genetic variability on the risk of developing malignant mesothelioma

Autor:	Franko Alenka, Kotnik Nika, Goricar Katja, Kovac Viljem, Dodic-Fikfak Metoda, Dolzan Vita
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	antioxidative enzymes genetic polymorphism malignant mesothelioma Medical physics. Medical radiology. Nuclear medicine R895-920
Zdroj:	Radiology and Oncology, Vol 52, Iss 1, Pp 105-111 (2018)
Druh dokumentu:	article
ISSN:	1581-3207 2018-0004
DOI:	10.2478/raon-2018-0004
Popis:	Malignant mesothelioma is a rare cancer with poor outcome, associated with asbestos exposure. Reactive oxygen species may play an important role in the mechanism of carcinogenesis; therefore, genetic variability in antioxidative defence may modify an individual’s susceptibility to this cancer. This study investigated the influence of functional polymorphisms of NQO1, CAT, SOD2 and hOGG1 genes, gene-gene interactions and gene-environment interactions on malignant mesothelioma risk.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e9e55ce4a3cd4160b04ca6800b8bf087 Zobrazit plný text záznamu View record in DOAJ