| Autor: |
L.A. Rodríguez de Antonio, P. Martínez-Sánchez, M.M. Martínez-Martínez, R. Cazorla-García, I. Sanz-Gallego, B. Fuentes, E. Díez-Tejedor |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Neurología (English Edition), Vol 26, Iss 3, Pp 150-156 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
2173-5808 |
| DOI: |
10.1016/S2173-5808(11)70031-1 |
| Popis: |
Introduction: Clinical and laboratory studies have attributed an inmuno-supressor effect to the statins. Furthermore, the administration of simvastatin in the acute onset of stroke has been associated with an increased infection frequency. Our objective is to assess the influence of statins previous treatment on infection after ischemic stroke. Patients and methods: Observational study of patients with ischaemic stroke hospitalised in a Stroke Unit. Demographic data, vascular risk factors, stroke severity, stroke subtype and previous statins treatment were evaluated. The following infections were registered: pneumonia, urinary tract infection, pseudomembranous colitis and sepsis. The patients were classified into two groups, depending on previous statin treatment. Results: A total of 2045 patients were included (1165 were male, aged 69.05 ± 12.5 years). Of these, 306 (15%) patients were receiving statins prior to stroke. These patients had more frequently arterial hypertension, DM, peripheral arterial disease and hypercholesterolaemia than the patients who were not treated with statins (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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