| Autor: |
Wenli Ruan, Shuoheng Shen, Yang Xu, Na Ran, Heng Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 86, Iss , Pp 104683- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2021.104683 |
| Popis: |
Neurodegenerative diseases such as Alzheimer's disease are characterized by the progressive, irreversible degeneration of central nervous system structure and function. As the global population ages, an increasing number of patients are being diagnosed with neurodegenerative diseases, for which there are still no curative drugs or treatments. Procyanidins are polyphenolic compounds widely found in plants such as grapes, blackberries, and hawthorn leaves. Procyanidins have been shown to have potential protective roles in neurodegenerative diseases by reducing oxidative stress, inhibiting neuroinflammation, and reducing the aggregation of abnormal proteins. This review summarizes the effects and underlying mechanisms of procyanidins in preventing and treating Alzheimer's disease, and in doing so we highlight that procyanidins represent an exciting new therapeutic strategy for neurodegenerative diseases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect