CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS
| Autor: | N N Kuzmina, B P Shokh, I L Nikishina |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Научно-практическая ревматология, Vol 38, Iss 2, Pp 56-62 (2000) |
| Druh dokumentu: | article |
| ISSN: | 1995-4484 1995-4492 |
| DOI: | 10.14412/1995-4484-2000-1234 |
| Popis: | Aim: To present modern approaches to the systemic therapy by glucocorticosteroids (GCS) basing on own experience and literature data. Methods and material: Long-term observation of 350 patients with juvenile rheumatoid arthritis (JRA) taking peroral GCS in different dosage. Results: Good therapeutical efficacy and sufficient tolerability of low starting doses (lower than 0.5 mg/ kg a day) of GCS allow to inhibit inflammatory activity in the majority of patients. Alternative method (doses alternation) is recommended in the period of long-term supporting GCS-therapv of JR.4. Conclusion: Basic strategy of treatment of systemic and polyarticular JRA j'orms is rational GCS application in combination with basic drugs which ensures control of pathologic process and modifies the disease. |
| Databáze: | Directory of Open Access Journals |
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