Real-world analysis of brain atrophy in multiple sclerosis patients with an artificial intelligence based software tool

Autor:	Caroline Reinhardt, Klemens Angstwurm, David Freudenstein, De-Hyung Lee, Christina Wendl, Ralf A. Linker
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Multiple sclerosis Brain atrophy Magnetic resonance imaging MR volumetry Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Zdroj:	Neurological Research and Practice, Vol 6, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	2524-3489
DOI:	10.1186/s42466-024-00339-y
Popis:	Abstract Background Atrophy of white and grey matter volumes occurs early in the brains of people with multiple sclerosis (pwMS) and has great clinical relevance. In clinical trials, brain atrophy can be quantified by magnetic resonance imaging (MRI) with automated software tools. Methods In this study, we analyze volumes of various brain regions with the software “md brain” based on routine MRI scans of 53 pwMS in a real-world setting. We compare brain volumes of pwMS with an EDSS ≥ 3.5 and a disease duration ≥ 10 years to the brain volumes of pwMS with an EDSS
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9e221952a13b48089f62560aa46bc4f4 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ