| Autor: |
Xiaoxiao Shan, Caiyun Zhang, Chutian Mai, Xuerui Hu, Nuo Cheng, Weidong Chen, Daiyin Peng, Lei Wang, Zhaojie Ji, Ying Xie |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Frontiers in Molecular Biosciences, Vol 8 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2296-889X |
| DOI: |
10.3389/fmolb.2021.715461 |
| Popis: |
Macrophage-derived exosomes have been implicated on the modulation of inflammatory processes. Recent studies have shown that macrophage-derived exosomes contribute to the progression of many diseases such as cancer, atherosclerosis, diabetes and heart failure. This review describes the biogenesis of macrophage-derived exosomes and their biological functions in different diseases. In addition, the challenges facing the use of macrophage-derived exosomes as delivery tools for drugs, genes, and proteins in clinical applications are described. The application of macrophage-derived exosomes in the diagnosis and treatment of diseases is also discussed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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