New sights into new‐onset and relapsed minimal change disease post COVID‐19 vaccination: A systemic review of the clinical characteristics and underlying pathogenesis

Autor: Jiarong Liu, Gaosi Xu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Rheumatology & Autoimmunity, Vol 4, Iss 3, Pp 145-155 (2024)
Druh dokumentu: article
ISSN: 2767-1429
2767-1410
DOI: 10.1002/rai2.12126
Popis: Abstract Background Minimal change disease (MCD) following coronavirus disease 2019 (COVID‐19) vaccination has been increasingly reported; however, the clinical characteristics and pathogenesis of patients with MCD have not been thoroughly discussed. Methods A systematic literature search of published data up until May 10, 2023, was conducted using the PubMed, Embase, Cochrane Library, Web of Science, and SinoMed databases. MCD patients diagnosed by renal biopsy following COVID‐19 vaccination were analyzed with the largest sample size to date. Results A total of 85 patients were included in the present statistical analysis, including 50 new‐onset and 35 relapsed MCD subjects following COVID‐19 vaccination. Compared with new‐onset MCD patients, the relapsed patients had previously suffered from one or two other diseases (12/50 vs. 34/35, p
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