Psoas muscle index in sarcopenia following transjugular intrahepatic portosystemic shunt: A multicenter, retrospective study

Autor: Tongqiang Li, Ze Wang, Yang Liu, Liguo Dai, Xiaoli Zhu, Jiacheng Liu, Qikun Guo, Weijie Luo, Yaowei Bai, Wei Luo, Menglan Chu, Duiping Feng, Bin Xiong
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Portal Hypertension & Cirrhosis, Vol 3, Iss 4, Pp 173-183 (2024)
Druh dokumentu: article
ISSN: 2770-5846
2770-5838
DOI: 10.1002/poh2.94
Popis: Abstract Aims Although the skeletal muscle index at the third lumbar vertebra (L3‐SMI) is commonly utilized for the diagnosis of sarcopenia, the psoas muscle index at L3 (L3‐PMI) may serve as a reliable alternative indicator. This study aims to investigate the application of the PMI in patients who have undergone transjugular intrahepatic portosystemic shunt (TIPS). Methods This study included a cohort of 406 patients with cirrhosis who underwent TIPS between February 2016 and July 2022 across three medical centers in China. Clinical and imaging data, specifically L3‐SMI and L3‐PMI, were collected for these patients. The prognosis of the patients was assessed through re‐examinations and telephone follow‐ups, which extended up to 5 years. The diagnostic thresholds for sarcopenia, as defined by L3‐PMI and L3‐SMI, were established at 6.36 or 42.00 cm²/m² for males and 3.92 or 38.00 cm²/m² for females, respectively. Cox proportional hazards and Kaplan–Meier (K‐M) analyses were employed to evaluate patient survival. Results The findings indicated that both L3‐PMI and L3‐SMI before TIPS were independent risk factors for mortality. The results of the paired t‐test demonstrated a significant increase in L3‐PMI 1 month post‐TIPS (5.11 ± 1.81 vs. 5.71 ± 1.90 cm²/m², p
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