Mini review (Part I): An experimental concept on exercise and ischemic conditioning in stroke rehabilitation

Autor: Qingzhu Wang, Melissa Wills, Zhenzhen Han, Xiaokun Geng, Yuchuan Ding
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Brain Circulation, Vol 6, Iss 4, Pp 242-247 (2020)
Druh dokumentu: article
ISSN: 2455-4626
DOI: 10.4103/bc.bc_63_20
Popis: Stroke remains a leading cause of adult death and disability. Poststroke rehabilitation is vital for reducing the long-term sequelae of brain ischemia. Recently, physical exercise training has been well established as an effective rehabilitation tool, but its efficacy depends on exercise parameters and the patient's capacities, which are often altered following a major cerebrovascular event. Thus, ischemic conditioning as a rehabilitation intervention was considered an “exercise equivalent,” but the investigation is still in its relative infancy. In this mini-review, we discuss the potential for physical exercise or ischemic conditioning and its relation to angiogenesis, neurogenesis, and plasticity in stroke rehabilitation. This allows the readers to understand the context of the research and the application of ischemic conditioning in poststroke rehabilitation.
Databáze: Directory of Open Access Journals