| Autor: |
Marcos F. DosSantos, Sylvie Devalle, Veronica Aran, Daniela Capra, Natália Roberta Roque, Juliana de Mattos Coelho-Aguiar, Tânia Cristina Leite de Sampaio e Spohr, Janice Gonçalves Subilhaga, Cláudia Maria Pereira, Isabella D'Andrea Meira, Paulo Niemeyer Soares Filho, Vivaldo Moura-Neto |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Frontiers in Neuroanatomy, Vol 14 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1662-5129 |
| DOI: |
10.3389/fnana.2020.00037 |
| Popis: |
Recent studies have suggested the neuroinvasive potential of severe acute respiratory coronavirus 2 (SARS-CoV-2). Notably, neuroinvasiveness might be involved in the pathophysiology of coronavirus disease 2019 (COVID-19). Some studies have demonstrated that synapse-connected routes may enable coronaviruses to access the central nervous system (CNS). However, evidence related to the presence of SARS-CoV-2 in the CNS, its direct impact on the CNS, and the contribution to symptoms suffered, remain sparse. Here, we review the current literature that indicates that SARS-CoV-2 can invade the nervous system. We also describe the neural circuits that are potentially affected by the virus and their possible role in the progress of COVID-19. In addition, we propose several strategies to understand, diagnose, and treat the neurological symptoms of COVID-19. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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