Comparison of Friedewald, Martin/Hopkins, and Sampson formulae with direct LDL measurement in hyperlipidaemic and normolipidaemic adults in a Turkish population

Autor: Alpdemir Medine, Alpdemir Mehmet Fatih, Şeneş Mehmet
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Medical Biochemistry, Vol 43, Iss 5, Pp 671-680 (2024)
Druh dokumentu: article
ISSN: 1452-8258
1452-8266
DOI: 10.5937/jomb0-46549
Popis: In our study, we aimed to compare the Friedewald, Martin/Hopkins, and Sampson formulae with direct LDL-cholesterol (d-LDL-C) measurement. Methods: The study was a retrospective investigation by the Department of Medical Biochemistry of the Ankara Training and Research Hospital between January 1, 2021, and December 31, 2022. Our study evaluated the results of 6297 patients aged 18-95 years who underwent cholesterol panel TC, TG, HDL-C, and direct LDL-C in our laboratory. The estimated LDL-C was calculated according to Friedewald, Martin/Hopkins, and Sampson formulae. Results: All three formulae showed a stronger positive correlation with d-LDL-C (0.905, 0.897, and 0.886, respectively, for all data, p
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