Low serum total testosterone level as a predictor of upgrading in low-risk prostate cancer patients after radical prostatectomy: A systematic review and meta-analysis

Autor: Shu Gan, Jian Liu, Zhiqiang Chen, Songtao Xiang, Chiming Gu, Siyi Li, Shusheng Wang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Investigative and Clinical Urology, Vol 63, Iss 4, Pp 407-414 (2022)
Druh dokumentu: article
ISSN: 2466-0493
2466-054X
DOI: 10.4111/icu.20210459
Popis: Purpose: To investigated the association between serum total testosterone and Gleason score upgrading of low-risk prostate cancer after radical prostatectomy (RP). Materials and Methods: Medline, Web of Science, Embase, and Cochrane Library databases were searched to identify eligible studies published before October 2021. Multivariate adjusted odds ratios (ORs) and associated 95% confidence intervals (CIs) were calculated using random or fixed effects models. Results: Five studies comprising 1,203 low-risk prostate cancer patients were included. The results showed that low serum total testosterone (
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