Transarterial Chemoembolization Of Hepatocellular Carcinoma: Can Early Diffusion Weighted Imaging Predict Response?

Autor: Asma Gulzar, Tahleel Shera, Omair Ashraf Shah, Naseer Choh, Tariq Gojwari, Mudasir Bhat, Shadab Maqsood
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Basic & Clinical Cancer Research, Vol 13, Iss 1 (2021)
Druh dokumentu: article
ISSN: 2228-6527
2228-5466
Popis: Background: We evaluated the role of early diffusion weighted imaging (DWI) in predicting response to TACE in patients with HCC and compare the results with contrast enhanced magnetic resonance imaging. METHODS: 24 patients with documented HCC were taken up for TACE after a pre-procedural contrast CT and MRI. Post procedural DWI was taken on day 5-7 and the mean ADC values were documented and compared to pre procedural values. The change in ADC values was grouped into 4 categories: group 1- 75%. The increase in ADC values signifying response was correlated with 5 week CEMRI scan and a threshold ADC increase signifying response in majority of the cases was calculated. RESULTS: The mean ADC of the lesions changed from 1.21× 10-3 (pre TACE) to 2.02× 10-3 mm2/sec (post TACE) [p
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