Autor: |
Theophilus Ogochukwu Nwankwo, Uchenna Anthony Umeh, Uzochukwu Uzoma Aniebue, Justus Uchenna Onu, Chioma Roseline Umeh |
Jazyk: |
English<br />French |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
The Pan African Medical Journal, Vol 36, Iss 210 (2020) |
Druh dokumentu: |
article |
ISSN: |
1937-8688 |
DOI: |
10.11604/pamj.2020.36.210.24141 |
Popis: |
There is paucity of data on interventions to improve cancer outcome in the low-resource setting. This study aims to determine the effect of Neoadjuvant Chemotherapy (NACT) in improving operative outcomes of cervical cancer. This was a longitudinal intervention study of patients diagnosed with FIGO stage IIB - IIIA cervical cancer that had NACT. Patients were re-evaluated after treatment with 4 cycles of chemotherapy for operability. McNemar test was used to determine changes in operability of the tumour. There was a significant difference in the number of patients that converted from inoperable to operable tumor post-chemotherapy. This study shows some promise for NACT for FIGO stage IIB - IIIA cancer of the cervix, especially in low-resource settings, where radiotherapy is scarce. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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