POEMS-syndrome: diagnostic difficulties

Autor: P. A. Lebedev, E. V. Paranina, V. A. Rossiyev, E. Y. Fedorova, A. S. Nikolaeva
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Терапевтический архив, Vol 92, Iss 7, Pp 104-108 (2020)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
00403660
DOI: 10.26442/00403660.2020.07.000596
Popis: POEMS syndrome is a rare paraneoplastic syndrome whose name is an acronym formed from the initial letters of the names of the symptoms originally used to determine it: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. Due to the rarity of the disease and the small number of cases described in the literature, its diagnosis is difficult. The average time from onset of symptoms to diagnosis is 18 months. Moreover, the prognosis of the disease depends on the early onset of specific treatment. The article describes a clinical case of POEMS-syndrome in a 53-year-old man, which illustrates the difficulties associated with the timely recognition of this unusual disease.
Databáze: Directory of Open Access Journals