Effect of Hydroalcoholic Extract of Lactuca Serriola on Blood Glucose in Streptozotocin (STZ)- Induced Diabetic the Rats
| Autor: | F Mohamad janni, K Roshanai, N Heydarieh |
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| Jazyk: | perština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 24, Iss 2, Pp 147-155 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2228-5741 2228-5733 |
| Popis: | Introduction: Diabetes mellitus (DM) is a disorder caused by abnormal insulin secretion and is diagnosed by the presence of hyperglycemia. Insulin is one of the drugs used by diabetics patients .This drug also like other drugs has side effects, but in this way using herbal medicine is more effective. This study is to determine the effect of hydroalcoholic extract of Lactuca serriola on blood glucose in Streptozotocin (STZ)- induced diabetic male rats. Methods: In study of 30 rats with an average weight of 200-230 g were divided into 5 groups consisted of 6 rats in each group comprised control, diabetic control and 3 groups treated orally with extract of Lactuca serriola. Diabetes was induced by STZ injection (IP) at a dose of 50mg/kg. The doses of 250,350 and 450 mg/kg of extract were injected intraperitoneally during 6 weeks (40 days). The data were analyzed by one way variance analysis and Tukey’s test using SPSS Version 17 (p |
| Databáze: | Directory of Open Access Journals |
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