Autor: |
Masahiro Matsuki, Toshiaki Tanaka, Takeshi Maehana, Koji Ichihara, Masahiro Yanase, Masanori Matsukawa, Hideki Adachi, Satoshi Takahashi, Naoya Masumori |
Jazyk: |
angličtina |
Rok vydání: |
2015 |
Předmět: |
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Zdroj: |
Asian Journal of Urology, Vol 2, Iss 3, Pp 167-169 (2015) |
Druh dokumentu: |
article |
ISSN: |
2214-3882 |
DOI: |
10.1016/j.ajur.2015.07.003 |
Popis: |
Objective: Recently, serum cystatin C (CysC) has been used as a novel marker of renal function. However, there is a lack of data on CysC levels in patients with intestinal urinary diversion (UD). Here we report CysC levels in such patients. Methods: We prospectively observed 38 patients who were diagnosed with bladder cancer and subsequently treated with radical cystectomy and UD at our institution in 2012 and 2013. Serum creatinine (sCr) and CysC were obtained optionally at the same time at least 1 month after radical cystectomy and UD. Results: The median CysC and sCr concentrations were 1.12 mg/L (range 0.75–2.47 mg/L) and 0.99 mg/dL (range 0.61–2.22 mg/dL), respectively. The median estimated concentrations of glomerular filtration rate (GFR) based on CysC (eGFRcys) and GFR based on creatinine (eGFRcreat) were 61.08 mL/min/1.73 m2 (range 22.64–99.89 mL/min/1.73 m2) and 58.01 mL/min/1.73 m2 (range 23.48–91.82 mL/min/1.73 m2), respectively. CysC had a significant correlation with sCr (r = 0.8607, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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