Experience of treatment of hairy cell leukemia with new drug Vero-cladribine

Autor:	Yu. E. Ryabukhina, A. D. Shirin, O. L. Timofeeva, N. N. Tupitsyn, M. A. Frenkel, N. A. Kupryshina, M. A. Volkova
Jazyk:	ruština
Rok vydání:	2022
Předmět:	hairy cell leukaemia treatment cladribine 2-chlorodeoxyadenosine Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Онкогематология, Vol 0, Iss 1, Pp 31-37 (2022)
Druh dokumentu:	article
ISSN:	1818-8346 2413-4023
DOI:	10.17650/1818-8346-2007-0-1-31-37
Popis:	Between July 2005and October 2006, eight patients (pts) with hairy cell leukaemia were treated with Vero- cladribine at N.N. Blokhin Cancer Research Center. All pts achieved complete remission (CR). Duration of CR ranges from 1+ to 12+ months in 7 cases. There were no serious adverse events during the treatment and follow-up periods (1-12 months). Vero- cladribine was well tolerated. Anemia (grade IV) was seen in 1 patient and thrombocytopenia (grade I) was seen in another 1 patient. No one patient has febrile neutropenia or infectious complication.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9d9cb8e84d6349099381d81d3d645393 Zobrazit plný text záznamu View record in DOAJ