Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction

Autor: Gabriela Servín-García, Luis Chacón-García, Joaquín González-Marrero, Mariana Macías-Alonso, Mario A. Gómez-Hurtado, Gabriela Rodríguez-García, Rosa E. del Río, Carlos J. Cortés-García
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chemistry Proceedings, Vol 12, Iss 1, p 24 (2022)
Druh dokumentu: article
ISSN: 2673-4583
DOI: 10.3390/ecsoc-26-13552
Popis: A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where a non-natural product such as 1,5-disusbtituted tetrazole has been linked to a natural product or derivate of a natural product, and beyond the biological relevance that the target molecules present, this work contributes to the area of natural products as well as multicomponent reactions.
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