Analysis of long-term outcomes of comprehensive treatment for coronary heart disease in patients with prediabetes and overt diabetes mellitus

Autor: Ya.Yu. Dzhun, G.B. Mankovsky, N.M. Rudenko
Jazyk: English<br />Ukrainian
Rok vydání: 2021
Předmět:
Zdroj: Mìžnarodnij Endokrinologìčnij Žurnal, Vol 17, Iss 2, Pp 121-126 (2021)
Druh dokumentu: article
ISSN: 2224-0721
2307-1427
DOI: 10.22141/2224-0721.17.2.2021.230566
Popis: Background. Despite modern methods for the diagnosis and treatment of impaired glucose metabolism, diabetes mellitus remains an independent risk factor and doubles the number of cardiovascular events (coronary heart disease, ischemic stroke, death). The effectiveness of modern methods for myocardial revascularization in patients with diabetes mellitus needs further researches. The purpose of this study is to evaluate risk factors and long-term outcomes of coronary artery revascularization in patients with coronary heart disease and concomitant prediabetes or overt diabetes mellitus. Materials and methods. This retrospective study involved 120 individuals with coronary heart disease who underwent revascularization of coronary arteries. Patients were divided into two groups according to the glycemic status: group I (main group) — prediabetes or diabetes mellitus (n = 58); group II (controls) — individuals without impaired glycemia (n = 62). Stenosis of coronary arteries was determined by coronary angiography. Treatment outcomes in both groups of patients were assessed as a progression of coronary artery atherosclerosis (repeated interventions caused by new atherosclerotic lesions or restenosis of preimplanted stent) and mortality rates. The average follow-up of patients in two groups is 3 years (minimum of 24 months). Results. Patients of group I predominantly had triple vessel disease (43.1 vs 16.1 %, p
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