Fetal Metabolic Alkalosis Resulting from Maternal Vomiting

Autor: William M. Curtin, Emily A. O'Brien, Rachel M. Mauro, Elizabeth A. Lucarelli-Baldwin, Serdar H. Ural, Christina T. DeAngelis
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: American Journal of Perinatology Reports, Vol 14, Iss 01, Pp e48-e50 (2024)
Druh dokumentu: article
ISSN: 2157-6998
2157-7005
DOI: 10.1055/s-0043-1778113
Popis: We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be related to hyperemesis gravidarum. Overtime, it became apparent that the patient induced vomiting by rapidly drinking large volumes of water. At 32 weeks' gestation, rapid ingestion of water caused 3 days of vomiting with findings of hyponatremia, hypokalemia, hypochloremia, metabolic alkalosis, and compensatory respiratory acidosis. Fetal monitoring showed minimal variability and recurrent decelerations; subsequent biophysical profile score of 2/10 prompted urgent cesarean section. A male newborn was delivered and cord blood gases reflected neonatal metabolic alkalosis and electrolyte imbalances identical to those of the mother. Compensatory hypoventilation in both mother and fetus were treated with assisted ventilation. With saline administration and repletion of electrolytes, metabolic alkalosis resolved for both patients within days.
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