Peginterferon-alpha 2a related peripheral neuropathy: A case report and review of the literature

Autor: Amalia Ghergu, Alexandra Oprisan, Cristina Mitu, Sorana Popescu, Oana Morari
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Romanian Journal of Neurology, Vol 16, Iss 3, Pp 119-122 (2017)
Druh dokumentu: article
ISSN: 1843-8148
2069-6094
DOI: 10.37897/RJN.2017.3.7
Popis: We report the case of a 46-year-old female with chronic hepatitis C virus infection who developed paresthesia and weakness of face and upper and lower extremities nine months after administration of peginterferon-alpha 2a. Considering her clinical evolution, neurological examination and nerve conduction studies, she was diagnosed with multifocal motor neuropathy related to peginterferon-alpha treatment. The patient recovered after use of intravenous immunoglobulins. From our knowledge there is no data in the literature about multifocal motor neuropathy related to peginterferon-alpha treatment. Doctors should be aware of this rare association, which requires immediate drug discontinuation and early management.
Databáze: Directory of Open Access Journals