Assessment of anti-inflammatory efficacy of acupuncture in patients with inflammatory bowel disease: A systematic review and meta-analysis

Autor: Xinyue Yang, Min He, Qingqing Tang, Zhihong Wang, De Jin, Xingquan Wu, Yonggang Yang, Dehui Ma, Mengmeng Sun, Tie Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Complementary Therapies in Medicine, Vol 74, Iss , Pp 102946- (2023)
Druh dokumentu: article
ISSN: 0965-2299
70356432
DOI: 10.1016/j.ctim.2023.102946
Popis: Background: Inflammation has a significant role in the onset and progression of inflammatory bowel disease (IBD). Increasing attention has been paid to the use of acupuncture in IBD patients; however, its regulatory effects on inflammatory factors in IBD still require validation. Here, we systematically evaluated the effects of acupuncture on inflammatory factors in IBD patients. Methods: Eight electronic databases were searched for studies that met the inclusion criteria. After evaluating the quality of the studies selected by two reviewers, the meta-analysis was performed to assess the efficacy of acupuncture in IBD patients and the impact on inflammatory factors (TNF-α, IL-1, IL-8 and IL-10). Results: Four randomized controlled trials with a total of 228 patients satisfied the inclusion criteria. Acupuncture has a positive therapeutic impact on IBD (MD = 1.22, 95% CI [1.07, 1.39], P = 0.003). Moreover, it regulates the levels of TNF-α (MD =−60.58, 95% CI [−100.30, −20.89], P = 0.003), IL-8 (MD =−56.40, 95% CI [−60.02, −52.14], P
Databáze: Directory of Open Access Journals
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