| Autor: |
Vasudha Meena, Durga Shankar Meena, Pradeep Singh Rathore, Sandeep Chaudhary, Jai Prakash Soni |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Annals of Pediatric Cardiology, Vol 13, Iss 2, Pp 130-135 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0974-2069 |
| DOI: |
10.4103/apc.APC_115_19 |
| Popis: |
Introduction: In this prospective study, we compared the efficacy and safety of ibuprofen, indomethacin, and paracetamol in the closure of patent ductus arteriosus (PDA) in preterm neonates. Materials and Methods: This randomized prospective study was conducted in the Division of Pediatric Cardiology, M. D. M and Umaid Hospital, Jodhpur. A total of 105 preterm neonates with gestational age 0.05). BUN and serum creatinine levels were significantly increased after treatment in indomethacin and ibuprofen groups (P < 0.0001 and P < 0.05, respectively). Conclusion: Our study shows that IV paracetamol is as effective as indomethacin and ibuprofen in promoting the closure of hs-PDA in premature infants with a better safety profile. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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