(25R)-16β-Acetoxy-3β-bromo-23′,26-epoxy-23′,25-dimethyl-5α-cholest-23,23′-en-6-one dichloromethane monosolvate
| Autor: | Susana Rincón, Rebeca Yépez, M. Eugenia Ochoa, Yliana López, Rosa Santillan, Norberto Farfán |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Acta Crystallographica Section E, Vol 68, Iss 12, Pp o3260-o3261 (2012) |
| Druh dokumentu: | article |
| ISSN: | 16005368 1600-5368 |
| DOI: | 10.1107/S1600536812043590 |
| Popis: | The crystal structure of the title compound, C31H45BrO5·CH2Cl2, prepared in six steps from diosgenin, confirmed that the configurations of the stereogenic centers, positions 20S and 25R, remain unchanged during the reaction. The six-membered A, B and C rings have chair conformations. The five-membered ring D has an envelope conformation (with the methyl-substituted C atom fused to ring C as the flap) and the six-membered dihydropyran ring E adopts a twist-boat conformation. In the crystal, molecules are linked via C—H...O and C—H...Cl hydrogen bonds, the latter involving the dichloromethane solvent molecule, forming a three-dimensional supramolecular network. |
| Databáze: | Directory of Open Access Journals |
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